616 Aortic stenosis: changing with age?
نویسندگان
چکیده
منابع مشابه
Aortic Stenosis: Changing Disease Concepts
Aortic stenosis (AS) occurs in almost 10% of adults over age 80 years with a mortality about 50% at 2 years unless outflow obstruction is relieved by aortic valve replacement (AVR). Development of AS is associated with anatomic, clinical and genetic risk factors including a bicuspid valve in 50%; clinical factors that include older age, hypertension, smoking, diabetes and elevated serum lipopro...
متن کاملSUPRAVALVAR AORTIC STENOSIS IN CHILDREN REPORT OF THIRTEEN CASES
During 15 years from 1975 to 1990, thirteen cases of supravalvar aortic stenosis were admitted at the pediatrics department of Shahid Rajai Heart Hospital, Tehran. All patients were subjected to cardiac catheterization and a angiocardiography. Patients ranged in age from 3.5 years to 14 years with a mean of 8.7 years. Seventy seven percent of childen were male. Eight cases (61.5%) had Wil...
متن کاملAge-associated aortic stenosis in apolipoprotein E-deficient mice.
OBJECTIVES The present study was designed to assess aortic valve morphology and function in mice of advanced age. We also evaluated the potential contribution of bone-marrow-derived cells to the pathogenesis of aortic stenosis. BACKGROUND Age-associated valvular degeneration is characterized by lipid accumulation, collagen deposition, and calcification containing smooth muscle-like cells and ...
متن کاملAortic Stenosis
The report from Belgium (1) and the accompanying editorial from Sweden (2) complain, rightly, that the published indications for intervention for asymptomatic severe aortic stenosis are in conflict. American guidelines (3) require a valve area 1 cm and a mean gradient 40 mm Hg, whereas Otto et al. (4) required a peak velocity 4 m/s that predicts a gradient of 64 mm Hg. The European guidelines (...
متن کاملAortic Stenosis.
This issue provides a clinical overview of aortic stenosis, focusing on screening, diagnosis, treatment, and practice improvement. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in col...
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ژورنال
عنوان ژورنال: European Heart Journal - Cardiovascular Imaging
سال: 2020
ISSN: 2047-2404,2047-2412
DOI: 10.1093/ehjci/jez319.303